Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.39 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21751074 | 1.00 | CRBN (0.50) | CRBNGPR139MAPTTHRBKMT2A | |
| SCHEMBL21751099 | 0.87 | CRBN (0.52) | CRBNMAPTTHRBKMT2ADDB1 | |
| SCHEMBL30600408 | 0.87 | CRBN (0.52) | CRBNMAPTTHRBKMT2ADDB1 | |
| SCHEMBL21751114 | 0.86 | CRBN (0.51) | CRBNMAPTKMT2ADDB1GSPT1 | |
| SCHEMBL30600393 | 0.86 | CRBN (0.51) | CRBNMAPTKMT2ADDB1GSPT1 | |
| SCHEMBL21751092 | 0.84 | CRBN (0.58) | CRBNDDB1GSPT1CYP2C19KCNH2 | |
| SCHEMBL21751105 | 0.83 | CRBN (0.56) | CRBNGPR139KMT2ADDB1GSPT1 | |
| SCHEMBL30600389 | 0.83 | CRBN (0.56) | CRBNGPR139KMT2ADDB1GSPT1 | |
| SCHEMBL30600416 | 0.81 | CRBN (0.47) | CRBNKMT2ADDB1GSPT1CYP2C19 | |
| SCHEMBL28357790 | 0.81 | CRBN (0.47) | CRBNKMT2ADDB1GSPT1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621664-B | Novel piperidine-2, 6-dione derivatives and uses thereof | 韩国化学研究院 | 2023-08-01 | — | — | CN | disclosed |