Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20516747 | 1.00 | MAP4K1 (0.79) | MAP4K1ABL1 | |
| SCHEMBL20517686 | 0.88 | MAP4K1 (0.67) | MAP4K1ABL1 | |
| SCHEMBL30600889 | 0.88 | MAP4K1 (0.67) | MAP4K1ABL1 | |
| SCHEMBL30210192 | 0.88 | MAP4K1 (1.00) | MAP4K1 | |
| SCHEMBL20516602 | 0.88 | MAP4K1 (1.00) | MAP4K1 | |
| SCHEMBL20516840 | 0.86 | MAP4K1 (0.81) | MAP4K1 | |
| SCHEMBL30600797 | 0.86 | MAP4K1 (0.81) | MAP4K1 | |
| SCHEMBL20516839 | 0.86 | MAP4K1 (0.81) | MAP4K1 | |
| SCHEMBL20517124 | 0.86 | MAP4K1 (0.78) | MAP4K1ABL1 | |
| SCHEMBL30600787 | 0.86 | MAP4K1 (0.78) | MAP4K1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024411-B | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-110709392-B | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2023-09-29 | — | — | CN | disclosed |