Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 13/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14811661 | 0.85 | AHR (0.81) | AHREGFR | |
| SCHEMBL30601215 | 0.82 | AHR (1.00) | AHRNPC1RAB9A | |
| SCHEMBL30288869 | 0.81 | AHR (0.68) | AHRNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL14811152 | 0.79 | AHR (0.65) | AHRALDH1A1MAPTHPGDHTT | |
| SCHEMBL24265214 | 0.77 | AHR (0.66) | AHRNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL30601227 | 0.76 | AHR (1.00) | AHRNPC1RAB9ASMN1; SMN2CYP11B2 | |
| SCHEMBL30601186 | 0.76 | AHR (1.00) | AHRNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL30601190 | 0.76 | AHR (1.00) | AHRNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL30601178 | 0.76 | AHR (0.60) | AHRNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL30601175 | 0.75 | AHR (0.73) | AHRNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514801-B | 2-Phenyl- [1,2,4] triazolo [1,5-a ] pyridine compound, nitrogen oxide thereof and application thereof | 四川大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-116514801-A | 2-phenyl- [1,2,4] triazolo [1,5-a ] pyridine compound, nitrogen oxide thereof and application thereof | 四川大学 | 2023-08-01 | — | — | CN | disclosed |