Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 13/20 | 0.52 |
| ▸ | MAOB | P27338 | 8/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22439215 | 1.00 | GRM5 (0.52) | GRM5MAOBMAOAPRMT5WDR77 | |
| SCHEMBL30922238 | 0.81 | PSMB5 (0.38) | GRM5PRMT5WDR77TDP2NSD2 | |
| SCHEMBL14661366 | 0.81 | PSMB5 (0.38) | GRM5PRMT5WDR77TDP2NSD2 | |
| SCHEMBL19153123 | 0.79 | GRM5 (0.55) | GRM5MAOBMAOANPC1ALDH1A1 | |
| SCHEMBL23160480 | 0.75 | FABP6 (0.42) | GRM5PRMT5WDR77 | |
| SCHEMBL18237776 | 0.75 | GRM5 (0.49) | GRM5MAOBMAOANPC1ALDH1A1 | |
| SCHEMBL30492966 | 0.73 | OGA (0.34) | PRMT5WDR77ALDH1A1 | |
| SCHEMBL23066271 | 0.73 | OGA (0.34) | PRMT5WDR77ALDH1A1 | |
| SCHEMBL30492969 | 0.73 | OGA (0.34) | PRMT5WDR77ALDH1A1 | |
| SCHEMBL2073931 | 0.72 | PRMT5 (0.46) | GRM5PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |