Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 1.00 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662542 | 0.92 | S1PR1 (1.00) | S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL3064884 | 0.91 | S1PR1 (0.98) | S1PR1S1PR3 | |
| SCHEMBL2991922 | 0.90 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL2994197 | 0.87 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL3051128 | 0.87 | S1PR1 (0.78) | S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL2988751 | 0.87 | S1PR1 (0.98) | S1PR1S1PR3 | |
| SCHEMBL12669606 | 0.86 | S1PR1 (0.81) | S1PR1S1PR3CYP2C9 | |
| Hydrochloric Acid SCHEMBL3066428 | 0.86 | S1PR1 (0.77) | S1PR1S1PR3 | |
| SCHEMBL13089015 | 0.86 | S1PR1 (0.75) | S1PR1S1PR3 | |
| SCHEMBL2995090 | 0.84 | S1PR1 (1.00) | S1PR1S1PR3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261767-A1 | OXADIAZOLE DERIVATIVES FOR USE AS S1P1 AGONISTS IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | HEER JAG PAUL | 2010-10-14 | — | — | US | claimed |
| US-20100261767-A1 | OXADIAZOLE DERIVATIVES FOR USE AS S1P1 AGONISTS IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | HEER JAG PAUL | 2010-10-14 | — | — | US | disclosed |
| US-20100261767-A1 | OXADIAZOLE DERIVATIVES FOR USE AS S1P1 AGONISTS IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | HEER JAG PAUL | 2010-10-14 | — | — | US | disclosed |
| US-20100261767-A1 | OXADIAZOLE DERIVATIVES FOR USE AS S1P1 AGONISTS IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | HEER JAG PAUL | 2010-10-14 | — | — | US | disclosed |
| EP-2222670-A1 | OXADIAZOLE DERIVATIVES FOR USE AS S1P1 AGONISTS IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | Glaxo Group Limited (GB) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009080729-A1 | OXADIAZOLE DERIVATIVES FOR USE AS S1P1 AGONISTS IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080729-A1 | OXADIAZOLE DERIVATIVES FOR USE AS S1P1 AGONISTS IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261767-A1 | OXADIAZOLE DERIVATIVES FOR USE AS S1P1 AGONISTS IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | S1PR1, S1PR3, S1PR5 | S1PR1 1/4885S1PR3 2/4885CYP2C9 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.