Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16073129 | 1.00 | MAPT (0.43) | MAPTSMN1; SMN2HSP90AA1HTTEPHX2 | |
| SCHEMBL16073143 | 0.90 | MAPT (0.44) | MAPTSMN1; SMN2HSP90AA1HTTPOLB | |
| SCHEMBL16043461 | 0.90 | EPHX2 (0.37) | MAPTSMN1; SMN2HSP90AA1HTTEPHX2 | |
| SCHEMBL16043462 | 0.90 | EPHX2 (0.37) | MAPTSMN1; SMN2HSP90AA1HTTEPHX2 | |
| SCHEMBL16073145 | 0.86 | MAPT (0.49) | MAPTSMN1; SMN2HSP90AA1HTTPOLB | |
| SCHEMBL16078614 | 0.86 | MAPT (0.49) | MAPTSMN1; SMN2HSP90AA1HTTPOLB | |
| SCHEMBL16073124 | 0.83 | CA12 (0.43) | MAPTPOLBHRH2HRH1CACNA2D1 | |
| SCHEMBL16073126 | 0.83 | MAPT (0.41) | MAPTSMN1; SMN2POLBHRH2HRH1 | |
| SCHEMBL20602061 | 0.82 | CYP1A2 (0.44) | MAPTPOLBHRH2HRH1KDM4E | |
| SCHEMBL16712033 | 0.82 | POLB (0.52) | MAPTSMN1; SMN2HSP90AA1HTTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970176-B1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2023-10-25 | — | — | EP | disclosed |