Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | CCNK | O75909 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CCND3 | P30281 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29085202 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL25738497 | 0.93 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29790206 | 0.91 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL22912808 | 0.91 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29085208 | 0.90 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL30604696 | 0.90 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29020731 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL30385197 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL22912831 | 0.87 | SMN1; SMN2 (0.65) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29396475 | 0.87 | SMN1; SMN2 (0.65) | SMN1; SMN2MAPTMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867783-A | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-10-10 | — | — | CN | disclosed |