Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14716754 | 1.00 | SYK (0.79) | SYKJAK2 | |
| SCHEMBL14716702 | 0.89 | SYK (0.86) | SYKJAK2 | |
| SCHEMBL30604971 | 0.88 | SYK (1.00) | SYKJAK2 | |
| SCHEMBL14717840 | 0.88 | SYK (1.00) | SYKJAK2 | |
| SCHEMBL14717482 | 0.88 | JAK2 (1.00) | SYKJAK2 | |
| SCHEMBL20376728 | 0.88 | SYK (0.79) | SYKJAK2 | |
| SCHEMBL14716846 | 0.88 | JAK2 (1.00) | SYKJAK2 | |
| SCHEMBL30604811 | 0.87 | SYK (0.88) | SYKJAK2 | |
| SCHEMBL26389942 | 0.87 | SYK (0.88) | SYKJAK2 | |
| SCHEMBL30605000 | 0.86 | SYK (1.00) | SYKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3392252-B1 | PYRIMIDO- PYRIDAZINONE COMPOUNDS AND USE THEREOF | LIBERTAS BIO INC (US) | 2023-10-04 | — | — | EP | claimed |
| EP-4327886-A2 | PYRIMIDO- PYRIDAZINONE COMPOUNDS AND USE THEREOF | Libertas Bio, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| EP-3392252-B1 | PYRIMIDO- PYRIDAZINONE COMPOUNDS AND USE THEREOF | LIBERTAS BIO INC (US) | 2023-10-04 | — | — | EP | disclosed |