Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26100982 | 1.00 | HPGD (0.58) | HPGDRAB9ANPC1SMN1; SMN2P2RX7 | |
| SCHEMBL21080890 | 0.94 | HPGD (0.52) | HPGDRAB9ANPC1SMN1; SMN2P2RX7 | |
| SCHEMBL21080891 | 0.94 | HPGD (0.52) | HPGDRAB9ANPC1SMN1; SMN2P2RX7 | |
| SCHEMBL31171408 | 0.90 | HPGD (0.51) | HPGDRAB9ANPC1SMN1; SMN2IRAK4 | |
| SCHEMBL21080597 | 0.89 | SMYD3 (0.48) | HPGDRAB9ANPC1SMN1; SMN2P2RX7 | |
| SCHEMBL21080599 | 0.89 | SMYD3 (0.48) | HPGDRAB9ANPC1SMN1; SMN2P2RX7 | |
| SCHEMBL31171348 | 0.88 | HPGD (0.47) | HPGDRAB9ANPC1SMN1; SMN2P2RX7 | |
| SCHEMBL30751129 | 0.87 | HPGD (0.46) | HPGDRAB9ANPC1KMT2A | |
| SCHEMBL21161737 | 0.87 | HPGD (0.46) | HPGDRAB9ANPC1KMT2A | |
| SCHEMBL31436626 | 0.83 | IRAK4 (0.53) | HPGDIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585250-A | KIT inhibitors | 蓝图药品公司 | 2025-03-07 | — | — | CN | disclosed |
| EP-4511366-A1 | KIT INHIBITORS | Blueprint Medicines Corporation (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023205226-A1 | KIT INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-10-26 | — | — | WO | disclosed |