SCHEMBL30607405

CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)[C@@H](C)CC)C(C)C)C(C)C)C(C)C)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)O

nearest known ligand 0.68

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	8/20	0.60

▸	NPY4R	P50391	8/20	0.60

▸	NPY5R	Q15761	8/20	0.60

▸	NPY1R	P25929	6/20	0.60

▸	CALCR	P30988	4/20	0.59

▸	EP300	Q09472	1/20	0.56

▸	HIF1A	Q16665	1/20	0.56

▸	CRHR1	P34998	1/20	0.55

▸	CRHR2	Q13324	1/20	0.55

▸	F2	P00734	2/20	0.54

▸	MAPK8	P45983	1/20	0.54

▸	MAPK9	P45984	1/20	0.54

▸	MAPK10	P53779	1/20	0.54

▸	KEAP1	Q14145	1/20	0.54

▸	TFPI	P10646	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30607381	0.90	NPY2R (0.68)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30495626	0.89	NPY2R (0.68)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30176506	0.89	NPY2R (0.63)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30658245	0.88	CALCR (0.71)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL29867615	0.88	CALCR (0.62)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31461996	0.87	CALCR (0.55)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30432324	0.87	F2 (0.62)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL29868039	0.87	CALCR (0.70)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30576894	0.87	CALCR (0.69)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30431820	0.87	CALCR (0.60)	NPY2RNPY4RNPY5RNPY1RCALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12383505-B2	Nanoparticle for the remodeling of cancer-associated fibroblasts	UNIVERSITY OF SOUTH CAROLINA (US)	2025-08-12	—	—	US	disclosed
US-20230310331-A1	NANOPARTICLE FOR THE REMODELING OF CANCER-ASSOCIATED FIBROBLASTS	UNIVERSITY OF SOUTH CAROLINA (US)	2023-10-05	—	—	US	disclosed