SCHEMBL30607488

CSCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](N)CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.70

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	EPHA2	P29317	2/20	0.64

▸	TFPI	P10646	4/20	0.60

▸	MC4R	P32245	1/20	0.59

▸	MC5R	P33032	1/20	0.59

▸	MC3R	P41968	1/20	0.59

▸	MC1R	Q01726	1/20	0.59

▸	C5AR1	P21730	1/20	0.57

▸	NPY2R	P49146	5/20	0.57

▸	NPY4R	P50391	5/20	0.57

▸	NPY5R	Q15761	5/20	0.57

▸	NPY1R	P25929	4/20	0.57

▸	CXCR4	P61073	4/20	0.57

▸	CALCR	P30988	2/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29489266	0.91	TFPI (0.64)	TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30186412	0.89	EPHA2 (0.65)	EPHA2TFPIMC4RMC5RMC3R
SCHEMBL31182744	0.89	NPY2R (0.67)	TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30296801	0.89	NPY2R (0.69)	TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30415361	0.89	EPHA2 (0.65)	EPHA2TFPIC5AR1NPY2RNPY4R
SCHEMBL30842159	0.88	NMUR2 (0.64)	EPHA2TFPIMC4RMC5RMC3R
SCHEMBL29805442	0.88	NPY2R (0.63)	TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30415378	0.87	TFPI (0.59)	EPHA2TFPIMC4RMC5RMC3R
SCHEMBL31295730	0.87	CALCR (0.61)	EPHA2TFPINPY2RNPY4RNPY5R
SCHEMBL29390108	0.87	EPHA2 (0.62)	EPHA2TFPIMC4RMC5RMC3R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12383505-B2	Nanoparticle for the remodeling of cancer-associated fibroblasts	UNIVERSITY OF SOUTH CAROLINA (US)	2025-08-12	—	—	US	disclosed
US-20230310331-A1	NANOPARTICLE FOR THE REMODELING OF CANCER-ASSOCIATED FIBROBLASTS	UNIVERSITY OF SOUTH CAROLINA (US)	2023-10-05	—	—	US	disclosed