SCHEMBL30607498

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CO)NC(=O)[C@@H](N)C(C)C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O

nearest known ligand 0.70

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	8/20	0.70

▸	NPY4R	P50391	8/20	0.70

▸	NPY5R	Q15761	8/20	0.70

▸	NPY1R	P25929	6/20	0.70

▸	CXCR4	P61073	3/20	0.64

▸	GLP1R	P43220	6/20	0.63

▸	IL23R	Q5VWK5	1/20	0.63

▸	MC4R	P32245	1/20	0.60

▸	MC5R	P33032	1/20	0.60

▸	MC3R	P41968	1/20	0.60

▸	MC1R	Q01726	1/20	0.60

▸	CCKBR	P32239	1/20	0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30567749	0.91	NPY2R (0.71)	NPY2RNPY4RNPY5RNPY1RGLP1R
SCHEMBL30607277	0.91	NPY2R (0.70)	NPY2RNPY4RNPY5RNPY1RGLP1R
SCHEMBL30607478	0.90	NPY2R (0.72)	NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL29901070	0.89	MC4R (0.65)	NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL30494418	0.89	NPY2R (0.67)	NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL30615288	0.89	CXCR4 (0.68)	NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL30658289	0.89	NPY2R (0.73)	NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL30277954	0.89	NPY2R (0.68)	NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL31000928	0.89	NPY2R (0.74)	NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL31000917	0.89	NPY2R (0.69)	NPY2RNPY4RNPY5RNPY1RCXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12383505-B2	Nanoparticle for the remodeling of cancer-associated fibroblasts	UNIVERSITY OF SOUTH CAROLINA (US)	2025-08-12	—	—	US	disclosed
US-20230310331-A1	NANOPARTICLE FOR THE REMODELING OF CANCER-ASSOCIATED FIBROBLASTS	UNIVERSITY OF SOUTH CAROLINA (US)	2023-10-05	—	—	US	disclosed