⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860150 | 0.64 | — | — | |
| SCHEMBL35325 | 0.64 | — | — | |
| SCHEMBL15104 | 0.61 | — | — | |
| SCHEMBL14439920 | 0.58 | — | — | |
| SCHEMBL1544800 | 0.58 | — | — | |
| SCHEMBL11790848 | 0.58 | — | — | |
| SCHEMBL96777 | 0.58 | — | — | |
| SCHEMBL2868165 | 0.58 | — | — | |
| SCHEMBL6220641 | 0.58 | — | — | |
| SCHEMBL9751214 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10421722-B2 | Sulfur-containing compounds targeting vesicular acetylcholine transporter | WASHINGTON UNIVERSITY (US) | 2019-09-24 | — | — | US | claimed |
| US-20170355675-A1 | SULFUR-CONTAINING COMPOUNDS TARGETING VESICULAR ACETYLCHOLINE TRANSPORTER | WASHINGTON UNIVERSITY (US) | 2017-12-14 | — | — | US | claimed |
| US-8497260-B2 | 2-arylbenzothiophene derivatives or pharmaceutically acceptable salts thereof, preparation method thereof, and pharmaceutical composition for the diagnosis or treatment of degenerative brain disease containing the same as active ingredient | Industry-University Cooperation Foundation Sogang University (KR) | 2013-07-30 | — | — | US | claimed |
| US-20100261727-A1 | 2-ARYLBENZOTHIOPHENE DERIVATIVES OR PHARCEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREOF, AND PHARCEUTICAL COMPOSITION FOR THE DIAGNOSIS OR TREATMENT OF DEGENERATIVE BRAIN DISEASE CONTAINING THE SAME AS ACTIVE INGREDIENT | Industry-University Cooperation Foundation Sogang University | 2010-10-14 | — | — | US | claimed |
| WO-2024053650-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST DIACYLGLYCEROL KINASE α AND/OR ζ, AND PHARMACEUTICAL USE THEREOF | 小野薬品工業株式会社 | 2024-03-14 | — | — | WO | disclosed |
| US-10421722-B2 | Sulfur-containing compounds targeting vesicular acetylcholine transporter | WASHINGTON UNIVERSITY (US) | 2019-09-24 | — | — | US | disclosed |
| US-20170355675-A1 | SULFUR-CONTAINING COMPOUNDS TARGETING VESICULAR ACETYLCHOLINE TRANSPORTER | WASHINGTON UNIVERSITY (US) | 2017-12-14 | — | — | US | disclosed |
| US-8497260-B2 | 2-arylbenzothiophene derivatives or pharmaceutically acceptable salts thereof, preparation method thereof, and pharmaceutical composition for the diagnosis or treatment of degenerative brain disease containing the same as active ingredient | Industry-University Cooperation Foundation Sogang University (KR) | 2013-07-30 | — | — | US | disclosed |
| US-20100261727-A1 | 2-ARYLBENZOTHIOPHENE DERIVATIVES OR PHARCEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREOF, AND PHARCEUTICAL COMPOSITION FOR THE DIAGNOSIS OR TREATMENT OF DEGENERATIVE BRAIN DISEASE CONTAINING THE SAME AS ACTIVE INGREDIENT | Industry-University Cooperation Foundation Sogang University | 2010-10-14 | — | — | US | disclosed |