SCHEMBL3060815

SCHEMBL3060815

NC(=O)CCn1cnc2c(=O)[nH]cnc21

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 16/20 0.63
PNP P00491 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7374581 0.87 HPRT1 (0.64) HPRT1PNP
SCHEMBL7397072 0.85 HPRT1 (0.59) HPRT1PNP
SCHEMBL7684892 0.82 HPRT1 (0.67) HPRT1PNP
SCHEMBL11258920 0.82 HPRT1 (0.69) HPRT1PNP
SCHEMBL7399531 0.81 HPRT1 (0.55) HPRT1PNP
SCHEMBL9533319 0.80 HPRT1 (0.64) HPRT1PNP
SCHEMBL7399609 0.79 HPRT1 (0.56) HPRT1PNP
SCHEMBL7393176 0.79 HPRT1 (0.53) HPRT1PNP
SCHEMBL20782416 0.79 HPRT1 (0.65) HPRT1PNP
SCHEMBL24239249 0.79 HPRT1 (0.63) HPRT1PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5091432-A Synergistic SPECTRUM PHARMACEUTICALS, INC. 1992-02-25 US claimed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 US disclosed