Sugi Predict

Sugi Predict / Compounds / SCHEMBL30608581

SCHEMBL30608581

SCHEMBL30608581

CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 2/20 0.55
▸ CTSB P07858 2/20 0.55
▸ KISS1R Q969F8 4/20 0.52
▸ TACR1 P25103 1/20 0.52
▸ DPP3 Q9NY33 3/20 0.51
▸ GLP1R P43220 6/20 0.51
▸ GIPR P48546 6/20 0.51
▸ NTSR2 O95665 1/20 0.51
▸ NTSR1 P30989 1/20 0.51
▸ SORT1 Q99523 1/20 0.51
▸ CXCL8 P10145 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30608592 0.96 CAPN1 (0.60) CAPN1CTSBGLP1RGIPRNTSR2
SCHEMBL30608567 0.96 CAPN1 (0.60) CAPN1CTSBGLP1RGIPRNTSR2
SCHEMBL31057848 0.95 CAPN1 (0.59) CAPN1CTSBKISS1RGLP1RGIPR
SCHEMBL30608614 0.94 GRPR (0.56) CAPN1CTSBCXCL8
SCHEMBL30608605 0.94 GRPR (0.56) CAPN1CTSBCXCL8
SCHEMBL30608570 0.94 GRPR (0.56) CAPN1CTSBCXCL8
SCHEMBL30608625 0.92 CAPN1 (0.56) CAPN1CTSBGLP1RGIPRCXCL8
SCHEMBL30608568 0.92 GRPR (0.56) CAPN1CTSBNTSR2NTSR1SORT1
SCHEMBL30608559 0.92 CAPN1 (0.56) CAPN1CTSBKISS1RGLP1RGIPR
SCHEMBL30608566 0.91 CAPN1 (0.59) CAPN1CTSBKISS1RTACR1GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646232-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY Université de Genève (CH) 2025-11-12 — — EP claimed
WO-2024146707-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY UNIVERSITÉ DE GENÈVE (CH) 2024-07-11 — — WO claimed
EP-4646232-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY Université de Genève (CH) 2025-11-12 — — EP disclosed
US-20250090637-A1 METHODS OF INHIBITING CEREBRAL INFLAMMATION UNIVERSITÉ DE GENÈVE (CH) 2025-03-20 — — US disclosed
CN-112469429-B Use of CCR5 inhibitors in cancer treatment 奥立安生物技术瑞士有限责任公司 2025-02-14 — — CN disclosed
CN-112469430-B Method for inhibiting cerebral inflammation 日内瓦大学 2024-12-24 — — CN disclosed
WO-2024146707-A1 VARIANT LIGAND CONJUGATES FOR PAYLOAD DELIVERY UNIVERSITÉ DE GENÈVE (CH) 2024-07-11 — — WO disclosed
EP-3813870-B1 CCR5 INHIBITOR FOR USE IN TREATING CANCER ORION Biotechnology Switzerland Sarl (CH) 2023-11-15 — — EP disclosed
EP-3813869-B1 CCR5 INHIBITOR FOR USE IN TREATING A NEUROINFLAMMATORY DISORDER THAT INVOLVES CEREBRAL INFLAMMATION UNIV GENEVE (CH) 2023-10-18 — — EP disclosed
Send feedback