Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30346693 | 0.88 | KDM4E (0.44) | ESR1KCNH2KDM4E | |
| SCHEMBL29876592 | 0.84 | ESR1 (0.39) | ESR1KCNH2 | |
| SCHEMBL29416173 | 0.84 | ESR1 (0.39) | ESR1KCNH2 | |
| SCHEMBL25002312 | 0.83 | ESR1 (0.43) | ESR1KCNH2CYP3A4 | |
| SCHEMBL25729776 | 0.83 | ESR1 (0.40) | ESR1KCNH2CYP3A4 | |
| SCHEMBL26085021 | 0.81 | ESR1 (0.42) | ESR1KCNH2CYP3A4 | |
| SCHEMBL27421169 | 0.80 | ESR1 (0.43) | ESR1KCNH2CYP3A4 | |
| SCHEMBL23100714 | 0.80 | ESR1 (0.40) | ESR1KCNH2CYP3A4 | |
| SCHEMBL17858931 | 0.79 | ESR1 (0.52) | ESR1KCNH2CYP3A4 | |
| SCHEMBL23127014 | 0.77 | ESR1 (0.39) | ESR1KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964049-A | Estrogen receptor modulators | 里科瑞尔姆IP控股有限责任公司 | 2023-10-27 | — | — | CN | disclosed |