Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.67 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18109656 | 1.00 | TLR8 (0.67) | TLR8TLR7KCNH2 | |
| SCHEMBL18109655 | 1.00 | TLR8 (0.67) | TLR8TLR7KCNH2 | |
| SCHEMBL13975800 | 0.93 | KCNH2 (0.63) | TLR8TLR7KCNH2 | |
| SCHEMBL18605999 | 0.93 | KCNH2 (0.63) | TLR8TLR7KCNH2 | |
| SCHEMBL24384557 | 0.86 | KCNH2 (0.85) | TLR8TLR7KCNH2 | |
| SCHEMBL15502394 | 0.86 | KCNH2 (0.85) | TLR8TLR7KCNH2 | |
| SCHEMBL13975807 | 0.86 | KCNH2 (0.85) | TLR8TLR7KCNH2 | |
| SCHEMBL21325637 | 0.86 | KCNH2 (0.85) | TLR8TLR7KCNH2 | |
| SCHEMBL22806213 | 0.85 | TLR8 (0.73) | TLR8TLR7KCNH2 | |
| SCHEMBL19924220 | 0.85 | KCNH2 (0.55) | TLR8TLR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174960-B | Toll-like receptor modulating 4, 6-diamino-pyrido [3,2-D ] pyrimidine compounds | 吉利德科学公司 | 2023-10-10 | — | — | CN | disclosed |