Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 11/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24735417 | 1.00 | PDE10A (0.46) | PDE10AMAP4K4PTGER4FPR1FPR2 | |
| SCHEMBL24735586 | 1.00 | PDE10A (0.46) | PDE10AMAP4K4PTGER4FPR1FPR2 | |
| SCHEMBL29841524 | 1.00 | PDE10A (0.46) | PDE10AMAP4K4PTGER4FPR1FPR2 | |
| SCHEMBL24735424 | 1.00 | PDE10A (0.46) | PDE10AMAP4K4PTGER4FPR1FPR2 | |
| SCHEMBL30612346 | 0.91 | PDE10A (0.48) | PDE10A | |
| SCHEMBL24735175 | 0.91 | PDE10A (0.48) | PDE10A | |
| SCHEMBL30612361 | 0.88 | PDE10A (0.41) | PDE10AMAP4K4 | |
| SCHEMBL24735600 | 0.88 | PDE10A (0.41) | PDE10AMAP4K4 | |
| SCHEMBL18391586 | 0.85 | PDE10A (0.39) | PDE10AMAP4K4 | |
| SCHEMBL15652803 | 0.82 | MAP4K4 (0.48) | PDE10AMAP4K4PTGER4FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117042769-A | Substituted pyrrolopyrimidines and pyrazolopyrimidines as Bruton's Tyrosine Kinase (BTK) degrading agents | 冰洲石生物科技公司 | 2023-11-10 | — | — | CN | disclosed |