Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 6/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | BUB1 | O43683 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 5/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | DTYMK | P23919 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30613661 | 1.00 | EPHA2 (0.48) | EPHA2EPHB4ERBB2BUB1RET | |
| SCHEMBL26135698 | 0.91 | EPHA2 (0.40) | EPHA2EPHB4ERBB2SYKIRAK4 | |
| SCHEMBL30613657 | 0.85 | EPHA2 (0.46) | EPHA2EPHB4ERBB2BUB1RET | |
| SCHEMBL30613703 | 0.84 | EPHA2 (0.58) | EPHA2EPHB4ERBB2BUB1RET | |
| SCHEMBL30613693 | 0.82 | EPHA2 (0.46) | EPHA2EPHB4ERBB2BUB1RET | |
| SCHEMBL30613620 | 0.81 | EPHA2 (0.46) | EPHA2EPHB4ERBB2BUB1RET | |
| SCHEMBL30613621 | 0.81 | EPHA2 (0.46) | EPHA2EPHB4ERBB2BUB1RET | |
| SCHEMBL30613625 | 0.79 | EPHA2 (0.49) | EPHA2EPHB4ERBB2BUB1RET | |
| SCHEMBL31676480 | 0.78 | SYK (0.45) | EPHA2SYKIRAK4 | |
| SCHEMBL13482977 | 0.75 | EPHA2 (0.54) | EPHA2EPHB4ERBB2BUB1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504724-A1 | SPLEEN TYROSINE KINASE INHIBITORS | Uniquest Pty Limited (AU) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023193054-A1 | SPLEEN TYROSINE KINASE INHIBITORS | UNIQUEST PTY LTD (AU) | 2023-10-12 | — | — | WO | disclosed |