Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 17/20 | 0.63 |
| ▸ | EZH1 | Q92800 | 5/20 | 0.61 |
| ▸ | EED | O75530 | 4/20 | 0.61 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.61 |
| ▸ | RBBP4 | Q09028 | 3/20 | 0.60 |
| ▸ | AEBP2 | Q6ZN18 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | BRD2 | P25440 | 1/20 | 0.50 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.50 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2588502 | 1.00 | EZH2 (0.63) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL2588655 | 1.00 | EZH2 (0.63) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL30620958 | 1.00 | EZH2 (0.63) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL2592253 | 1.00 | EZH2 (0.63) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL12180154 | 0.93 | EED (0.56) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL16360915 | 0.93 | EZH2 (0.55) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL16360904 | 0.93 | EZH2 (0.55) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL16360914 | 0.92 | EZH2 (0.55) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL14717966 | 0.92 | EED (0.58) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL2592559 | 0.92 | EZH2 (0.64) | EZH2EZH1EEDSUZ12RBBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805350-B | Benzo heterocycle-pyridone derivative, and preparation method and application thereof | 四川大学华西医院 | 2023-10-20 | — | — | CN | disclosed |