Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 3/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21463404 | 1.00 | TNKS (0.46) | TNKSAOC3PIK3CAMTORHSP90AA1 | |
| SCHEMBL28492431 | 0.84 | AURKA (0.45) | TNKSPIK3CAMTORHSP90AA1HSP90AB1 | |
| SCHEMBL23927060 | 0.80 | TNKS (0.46) | TNKSDAOFEN1TGFBR1CYP1A2 | |
| SCHEMBL16456380 | 0.78 | TNKS (0.54) | TNKSDAOMAPTFEN1TGFBR1 | |
| SCHEMBL16657373 | 0.77 | TNKS (0.52) | TNKSDAOFEN1TGFBR1CYP1A2 | |
| SCHEMBL28490416 | 0.77 | DAO (0.47) | TNKSAOC3PIK3CAMTORHSP90AA1 | |
| SCHEMBL30615573 | 0.77 | DAO (0.47) | TNKSAOC3PIK3CAMTORHSP90AA1 | |
| SCHEMBL30257956 | 0.76 | TNKS (0.49) | TNKSDAOFEN1TGFBR1CYP1A2 | |
| SCHEMBL18425727 | 0.75 | TNKS (0.51) | TNKSAOC3DAOFEN1TGFBR1 | |
| SCHEMBL15552211 | 0.75 | MEN1 (0.52) | TNKSAOC3DAOFEN1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |