Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 1.00 |
| ▸ | PDCD1LG2 | Q9BQ51 | 15/20 | 1.00 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21507056 | 1.00 | CD274 (1.00) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL21507291 | 0.87 | CD274 (1.00) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL21506839 | 0.83 | CD274 (1.00) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL27081077 | 0.82 | CD274 (0.85) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL21506881 | 0.81 | CD274 (1.00) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL31622017 | 0.81 | CD274 (1.00) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL21497025 | 0.81 | CD274 (1.00) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL21291129 | 0.80 | CD274 (1.00) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL21507087 | 0.78 | CD274 (1.00) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL21274576 | 0.78 | CD274 (0.76) | CD274PDCD1LG2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041311-B | PD-1/PD-L1 inhibitors | 吉利德科学公司 | 2023-10-03 | — | — | CN | disclosed |