Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 20/20 | 0.63 |
| ▸ | SCN1A | P35498 | 19/20 | 0.63 |
| ▸ | SCN5A | Q14524 | 19/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20252561 | 1.00 | SCN8A (0.63) | SCN8ASCN1ASCN5ANR1I2SCN1B | |
| SCHEMBL20256353 | 0.94 | SCN1A (0.62) | SCN8ASCN1ASCN5A | |
| SCHEMBL20256648 | 0.94 | SCN8A (0.55) | SCN8ASCN1ASCN5A | |
| SCHEMBL20252683 | 0.91 | SCN8A (0.62) | SCN8ASCN1ASCN5A | |
| SCHEMBL20238781 | 0.90 | SCN1A (0.68) | SCN8ASCN1ASCN5ANR1I2SCN1B | |
| SCHEMBL20252671 | 0.89 | SCN8A (0.66) | SCN8ASCN1ASCN5A | |
| SCHEMBL20252560 | 0.89 | SCN8A (0.63) | SCN8ASCN1ASCN5ANR1I2SCN1B | |
| SCHEMBL20252652 | 0.87 | SCN8A (0.57) | SCN8ASCN1ASCN5ANR1I2SCN1B | |
| SCHEMBL20256757 | 0.86 | SCN1A (0.57) | SCN8ASCN1ASCN5ANR1I2SCN1B | |
| SCHEMBL20252679 | 0.86 | SCN8A (0.65) | SCN8ASCN1ASCN5ANR1I2SCN1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551626-B1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2023-10-25 | — | — | EP | disclosed |