Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.56 |
| ▸ | IKZF3 | Q9UKT9 | 6/20 | 0.52 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 2/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | IL1B | P01584 | 1/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.45 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.45 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962924 | 0.84 | CRBN (0.68) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL25653782 | 0.84 | CRBN (0.65) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL25726981 | 0.84 | CRBN (0.65) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL24765458 | 0.84 | CRBN (0.65) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL27289821 | 0.82 | CRBN (0.56) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL13641027 | 0.82 | CRBN (0.62) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL21107124 | 0.80 | CRBN (0.70) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL21107638 | 0.80 | CRBN (0.70) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL17299698 | 0.80 | CRBN (0.70) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL27289818 | 0.79 | CRBN (0.53) | CRBNIKZF3IKZF1BRD4TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088864-A | Benzo [ d ] isoxazole compound and application thereof | 广州智药生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| WO-2023217063-A1 | BENZO[D]ISOXAZOLE COMPOUND AND USE THEREOF | 广州智药生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |