SCHEMBL30620170

SCHEMBL30620170

CCCCCCOc1ccc(-c2ccc3c(c2)[nH]c2cc(-c4ccc(OCCCCCC)cc4F)ccc23)c(F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR17 Q13304 1/20 0.44
HTR1B P28222 9/20 0.44
HTR1D P28221 8/20 0.44
HTR1A P08908 6/20 0.44
PTPN11 Q06124 4/20 0.44
MAPT P10636 2/20 0.44
MAPK1 P28482 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
KDM4E B2RXH2 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
HTR2A P28223 1/20 0.44
CYP2C19 P33261 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MCL1 Q07820 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9244788 0.84 PTPN11 (0.54) PTPN11TP53CYP3A4CYP2D6MCL1
SCHEMBL9247693 0.84 PTPN11 (0.54) PTPN11TP53CYP3A4CYP2D6MCL1
SCHEMBL30620168 0.83 RARB (0.52) GPR17HTR1BHTR1DHTR1AMAPT
SCHEMBL9845134 0.82 PTPN11 (0.50) PTPN11MAPTMCL1ALDH2S1PR1
SCHEMBL13648658 0.81 PTPN11 (0.52) PTPN11MCL1ALDH2S1PR1S1PR3
SCHEMBL13648644 0.81 PTPN11 (0.52) PTPN11MCL1ALDH2S1PR1S1PR3
SCHEMBL11036498 0.81 NR5A1 (0.53) HTR1BHTR1DHTR1APTPN11MAPT
SCHEMBL26331612 0.79 NR5A1 (0.62) PTPN11MAPTMEN1KMT2AMCL1
SCHEMBL17447398 0.79 PTPN11 (0.54) PTPN11PDK2
SCHEMBL6657660 0.78 PTPN11 (0.49) HTR1BHTR1DHTR1APTPN11MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117165305-B Negative liquid crystal compound and preparation method and application thereof 陕西师范大学 2025-05-16 CN disclosed
CN-117165305-A Negative liquid crystal compound and preparation method and application thereof 陕西师范大学 2023-12-05 CN disclosed