SCHEMBL30620436

SCHEMBL30620436

CC(=O)Nc1ncc(CN2CCN(CC(=O)Nc3nc4ccccc4[nH]3)CC2)s1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 18/20 0.68
▸ LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27008633 1.00 OGA (0.68) OGALMNA
SCHEMBL29057506 0.86 OGA (0.48) OGALMNA
SCHEMBL26349079 0.82 OGA (0.72) OGA
SCHEMBL30620440 0.82 OGA (0.72) OGA
SCHEMBL27008585 0.81 OGA (1.00) OGA
SCHEMBL27008581 0.80 OGA (1.00) OGA
SCHEMBL27008587 0.79 OGA (1.00) OGA
SCHEMBL27008685 0.79 OGA (0.76) OGA
SCHEMBL27008568 0.79 OGA (0.72) OGALMNA
SCHEMBL27022304 0.78 OGA (0.92) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4249475-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLCNACASE AND USE THEREOF MEDIFRON DBT INC. (KR) 2023-09-27 — — EP claimed
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF MEDIFRON DBT INC. (KR) 2024-01-18 — — US disclosed
EP-4249475-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLCNACASE AND USE THEREOF MEDIFRON DBT INC. (KR) 2023-09-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF OGA, OGT, ENGASE OGA 1/4885LMNA 4199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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