Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 19/20 | 0.73 |
| ▸ | BCL2L1 | Q07817 | 18/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | BAD | Q92934 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622011 | 0.96 | BCL2L1 (0.70) | BCL2BCL2L1CYP2C9BAD | |
| SCHEMBL2724191 | 0.96 | BCL2L1 (0.70) | BCL2BCL2L1CYP2C9BAD | |
| SCHEMBL29796301 | 0.94 | BCL2 (0.69) | BCL2BCL2L1CYP2C9BAD | |
| SCHEMBL2726707 | 0.94 | BCL2 (0.69) | BCL2BCL2L1CYP2C9BAD | |
| SCHEMBL1869287 | 0.90 | BCL2 (0.68) | BCL2BCL2L1CYP2C9BAD | |
| SCHEMBL29796199 | 0.90 | BCL2 (0.68) | BCL2BCL2L1CYP2C9BAD | |
| SCHEMBL30314123 | 0.89 | BCL2 (0.60) | BCL2BCL2L1CYP2C9 | |
| SCHEMBL29796244 | 0.89 | BCL2 (0.60) | BCL2BCL2L1CYP2C9BAD | |
| SCHEMBL1872740 | 0.89 | BCL2 (0.61) | BCL2BCL2L1CYP2C9 | |
| SCHEMBL29796468 | 0.89 | BCL2 (0.61) | BCL2BCL2L1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435432-B3 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBVIE IRELAND UNLIMITED CO (BM) | 2023-10-25 | — | — | EP | disclosed |