Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634826 | 1.00 | KAT8 (0.57) | KAT8PPARAALDH1A1BCHEEP300 | |
| SCHEMBL2005845 | 0.99 | KAT8 (0.56) | KAT8PPARAALDH1A1BCHEEP300 | |
| SCHEMBL28055831 | 0.99 | KAT8 (0.56) | KAT8PPARAALDH1A1BCHEEP300 | |
| SCHEMBL8596017 | 0.88 | KAT8 (0.58) | KAT8PPARAALDH1A1BCHEEP300 | |
| Potassium Ion SCHEMBL7928665 | 0.87 | KAT8 (0.51) | KAT8PPARAALDH1A1BCHEEP300 | |
| SCHEMBL30206997 | 0.87 | KAT8 (0.51) | KAT8PPARAALDH1A1BCHEEP300 | |
| Lithium Ion SCHEMBL7919579 | 0.87 | KAT8 (0.51) | KAT8PPARAALDH1A1BCHEEP300 | |
| SCHEMBL7928563 | 0.87 | KAT8 (0.51) | KAT8PPARAALDH1A1BCHEEP300 | |
| SCHEMBL536515 | 0.87 | KAT8 (0.51) | KAT8PPARAALDH1A1BCHEEP300 | |
| SCHEMBL7925730 | 0.87 | KAT8 (0.51) | KAT8PPARAALDH1A1BCHEEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190315905-A1 | AMINE CATALYSTS FOR POLYURETHANE FOAMS | SOLSTICE ADVANCED MATERIALS US, INC. | 2019-10-17 | — | — | US | claimed |
| EP-3548533-A1 | POLYURETHANE RIGID FOAM, METHOD FOR PRODUCING SAME, AND USE THEREOF | Covestro Deutschland AG (DE) | 2019-10-09 | — | — | EP | claimed |
| EP-2770003-B1 | INSULATION MOULDING AND METHOD FOR ITS MANUFACTURE | COVESTRO DEUTSCHLAND AG (DE) | 2018-09-12 | — | — | EP | claimed |
| US-10066071-B2 | Stabilization of polyurethane foam polyol premixes containing halogenated olefin blowing agents | HONEYWELL INTERNATIONAL INC. (US) | 2018-09-04 | — | — | US | claimed |
| US-20170088662-A1 | AMINE CATALYSTS FOR POLYURETHANE FOAMS | HONEYWELL INTERNATIONAL INC. | 2017-03-30 | — | — | US | claimed |
| US-20170002166-A1 | STABILIZATION OF POLYURETHANE FOAM POLYOL PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS | SOLSTICE ADVANCED MATERIALS US, INC. | 2017-01-05 | — | — | US | claimed |
| US-9453115-B2 | Stabilization of polyurethane foam polyol premixes containing halogenated olefin blowing agents | HONEYWELL INTERNATIONAL INC. (US) | 2016-09-27 | — | — | US | claimed |
| EP-2744839-B1 | METHOD FOR MANUFACTURING A POLYURETHANE POLYISOCYANURATE RIGID FOAM | COVESTRO DEUTSCHLAND AG (DE) | 2016-02-24 | — | — | EP | claimed |
| EP-2812370-B1 | METHOD FOR PRODUCING A HARD POLYURETHANE-POLYISOCYANURATE FOAMED MATERIAL | COVESTRO DEUTSCHLAND AG (DE) | 2015-11-04 | — | — | EP | claimed |
| EP-2197935-B1 | STABILIZATION OF POLYURETHANE FOAM POLYOL PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS | HONEYWELL INT INC (US) | 2013-08-21 | — | — | EP | claimed |
| EP-2197935-A2 | STABILIZATION OF POLYURETHANE FOAM POLYOL PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS | Honeywell International Inc. (US) | 2010-06-23 | — | — | EP | claimed |
| EP-2197933-A2 | AMINE CATALYSTS FOR POLYURETHANE FOAMS | Honeywell International Inc. (US) | 2010-06-23 | — | — | EP | claimed |
| US-20090099273-A1 | NON-SILICONE SURFACTANTS FOR POLYURETHANE OR POLYISOCYANURATE FOAM CONTAINING HALOGENATED OLEFINS AS BLOWING AGENTS | HONEYWELL INTERNATIONAL INC. | 2009-04-16 | — | — | US | claimed |
| US-20090099272-A1 | STABILIZATION OF POLYURETHANE FOAM POLYOL PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS | SOLSTICE ADVANCED MATERIALS US, INC. | 2009-04-16 | — | — | US | claimed |
| WO-2009048826-A2 | STABILIZATION OF POLYURETHANE FOAM POLYOL PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS | HONEYWELL INTERNATIONAL INC. (US) | 2009-04-16 | — | — | WO | claimed |
| WO-2009048807-A2 | AMINE CATALYSTS FOR POLYURETHANE FOAMS | HONEYWELL INTERNATIONAL INC. (US) | 2009-04-16 | — | — | WO | claimed |
| US-20090099274-A1 | AMINE CATALYSTS FOR POLYURETHANE FOAMS | SOLSTICE ADVANCED MATERIALS US, INC. | 2009-04-16 | — | — | US | claimed |
| US-5844012-A | Process and composition for improving the cure of water-blown molded polyurethane foam | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-12-01 | — | — | US | claimed |
| EP-0445837-B1 | Crosslinkable polyester/isocyanate compositions suitable for the preparation of composite materials | SIR IND SPA (IT) | 1997-01-08 | — | — | EP | claimed |
| US-5382626-A | Formation of polyurethanes and crosslinking with vinyl groups and unsaturated polyesters | MONTEDISON S.P.A. (IT) | 1995-01-17 | — | — | US | claimed |