Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.62 |
| ▸ | BRD4 | O60885 | 3/20 | 0.59 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.58 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.58 |
| ▸ | TNF | P01375 | 1/20 | 0.58 |
| ▸ | IL1B | P01584 | 1/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.58 |
| ▸ | MAP1LC3B | Q9GZQ8 | 5/20 | 0.56 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16569451 | 1.00 | CRBN (0.62) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL19611888 | 0.94 | CRBN (0.55) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL19612074 | 0.94 | CRBN (0.55) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL22464461 | 0.94 | CRBN (0.60) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL464519 | 0.94 | CRBN (0.60) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL23772949 | 0.93 | CRBN (0.59) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL29137874 | 0.93 | CRBN (0.59) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL22464808 | 0.93 | CRBN (0.59) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL20362334 | 0.93 | CRBN (0.59) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL22464605 | 0.92 | CRBN (0.64) | CRBNBRD4IKZF3IKZF1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111205282-B | ER protein modulators and uses thereof | 上海科技大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-110240629-B | Protein degradation targeting BCR-ABL compound and antitumor application thereof | 上海科技大学 | 2023-10-03 | — | — | CN | disclosed |