Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 11/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628523 | 0.91 | EIF2AK4 (0.43) | EIF2AK4AURKAPDPK1AURKBJAK3 | |
| SCHEMBL30628494 | 0.90 | EIF2AK4 (0.42) | EIF2AK4AURKAPDPK1AURKBJAK3 | |
| SCHEMBL30628529 | 0.90 | EIF2AK4 (0.42) | EIF2AK4AURKAPDPK1AURKBJAK3 | |
| SCHEMBL30628521 | 0.89 | EIF2AK4 (0.42) | EIF2AK4AURKAPDPK1AURKBJAK3 | |
| SCHEMBL30628531 | 0.89 | EIF2AK4 (0.42) | EIF2AK4AURKAPDPK1AURKBJAK3 | |
| SCHEMBL30628504 | 0.89 | EIF2AK4 (0.42) | EIF2AK4AURKAPDPK1AURKBJAK3 | |
| SCHEMBL30628525 | 0.89 | EIF2AK4 (0.42) | EIF2AK4AURKAPDPK1AURKBJAK3 | |
| SCHEMBL30628513 | 0.88 | EIF2AK4 (0.41) | EIF2AK4AURKAPDPK1AURKBJAK3 | |
| SCHEMBL30628511 | 0.88 | EIF2AK4 (0.41) | EIF2AK4AURKAPDPK1AURKBJAK3 | |
| SCHEMBL26632154 | 0.87 | CHRM4 (0.41) | ALDH1A1MAPTLMNACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211256-A1 | NOVEL PIM KINASE INHIBITORS AND USES THEREOF | 제일약품주식회사 | 2023-11-02 | — | — | WO | disclosed |