Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 15/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 2/20 | 0.47 |
| ▸ | CCR7 | P32248 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 9/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13075315 | 1.00 | CXCR2 (0.57) | CXCR2GAACCR6CCR7MAPT | |
| SCHEMBL23610482 | 1.00 | CXCR2 (0.57) | CXCR2GAACCR6CCR7MAPT | |
| SCHEMBL30631989 | 0.91 | GAA (0.50) | CXCR2GAACCR6CCR7MAPT | |
| SCHEMBL21803167 | 0.91 | GAA (0.50) | CXCR2GAACCR6CCR7MAPT | |
| SCHEMBL21803030 | 0.89 | CXCR2 (0.49) | CXCR2GAACCR6CCR7MAPT | |
| SCHEMBL30631983 | 0.89 | CXCR2 (0.49) | CXCR2GAACCR6CCR7MAPT | |
| SCHEMBL23621373 | 0.81 | CXCR2 (0.56) | CXCR2CCR6CCR7CXCR1 | |
| SCHEMBL1707274 | 0.80 | CXCR2 (0.66) | CXCR2GAACCR6CXCR1 | |
| SCHEMBL12087066 | 0.79 | GAA (0.52) | CXCR2GAACCR6MAPTCXCR1 | |
| SCHEMBL14895045 | 0.78 | CCR6 (0.61) | CXCR2GAACCR6MAPTCXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874466-B | N-substituted dioxocyclobutylamino-3-hydroxy-pyridinecarboxamides as CCR6 inhibitors | PFIZER INC. (US) | 2026-05-26 | — | — | CN | disclosed |
| CN-116874466-A | N-substituted dioxocyclobutylamino-3-hydroxy-pyridinecarboxamides as CCR6 inhibitors | 辉瑞公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-112672791-B | N-substituted dioxocyclobutylamino-3-hydroxy-pyridinecarboxamides as CCR6 inhibitors | 辉瑞公司 | 2023-10-03 | — | — | CN | disclosed |