Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | SCD | O00767 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26606535 | 1.00 | MAPT (0.57) | MAPTKDM4EHPGDHSD17B10RXFP1 | |
| SCHEMBL26606514 | 0.90 | KDM4E (0.61) | MAPTKDM4EHPGDHSD17B10RXFP1 | |
| SCHEMBL26606567 | 0.86 | NPC1 (0.67) | MAPTKDM4ENPC1RAB9AMEN1 | |
| SCHEMBL26606544 | 0.86 | MAPT (0.58) | MAPTKDM4EHPGDHSD17B10RXFP1 | |
| SCHEMBL26606572 | 0.86 | MAPT (0.72) | MAPTKDM4EHPGDHSD17B10RXFP1 | |
| SCHEMBL26606496 | 0.85 | PCSK9 (0.59) | MAPTKDM4EHPGDHSD17B10RXFP1 | |
| SCHEMBL27193117 | 0.82 | ADORA2A (0.64) | MAPTKDM4EHPGDHSD17B10RXFP1 | |
| SCHEMBL26606555 | 0.82 | ADORA2A (0.58) | MAPTKDM4EHPGDHSD17B10RXFP1 | |
| SCHEMBL26606566 | 0.81 | MAPT (0.68) | MAPTKDM4EHPGDHSD17B10RXFP1 | |
| SCHEMBL26606460 | 0.81 | NPC1 (0.59) | MAPTKDM4EHPGDHSD17B10RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269394-A1 | BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2023-11-01 | — | — | EP | disclosed |