Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 14/20 | 0.52 |
| ▸ | WNT1 | P04628 | 9/20 | 0.50 |
| ▸ | CLK2 | P49760 | 4/20 | 0.50 |
| ▸ | CLK3 | P49761 | 4/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686348 | 1.00 | DYRK1A (0.52) | DYRK1AWNT1CLK2CLK3JAK2 | |
| SCHEMBL30633352 | 0.89 | JAK2 (0.56) | DYRK1ACLK2JAK2MAPK1KDR | |
| SCHEMBL26685861 | 0.89 | JAK2 (0.56) | DYRK1ACLK2JAK2MAPK1KDR | |
| SCHEMBL30633326 | 0.88 | DYRK1A (0.45) | DYRK1AWNT1CLK2CLK3JAK2 | |
| SCHEMBL31240466 | 0.85 | JAK2 (0.54) | DYRK1AWNT1CLK2CLK3JAK2 | |
| SCHEMBL30633365 | 0.85 | KDR (0.62) | DYRK1ACLK2JAK2MAPK1KDR | |
| SCHEMBL26686045 | 0.85 | KDR (0.57) | DYRK1ACLK2JAK2MAPK1KDR | |
| SCHEMBL30633305 | 0.85 | KDR (0.57) | DYRK1ACLK2JAK2MAPK1KDR | |
| SCHEMBL26685808 | 0.85 | KDR (0.62) | DYRK1ACLK2JAK2MAPK1KDR | |
| SCHEMBL30633343 | 0.84 | MAPK1 (0.54) | DYRK1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | claimed |
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |