Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | BUB1 | O43683 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686389 | 1.00 | MAPK8 (0.42) | MAPK8MAPK10BUB1PIK3C3ALDH1A1 | |
| SCHEMBL26686526 | 0.90 | PIK3C3 (0.39) | MAPK8MAPK10PIK3C3WNT3A | |
| SCHEMBL26686349 | 0.90 | PIK3C3 (0.41) | MAPK8MAPK10BUB1PIK3C3WNT3A | |
| SCHEMBL31420562 | 0.90 | PIK3C3 (0.41) | MAPK8MAPK10BUB1PIK3C3WNT3A | |
| SCHEMBL30633291 | 0.89 | PIK3C3 (0.51) | PIK3C3 | |
| SCHEMBL26888164 | 0.89 | PIK3C3 (0.51) | PIK3C3 | |
| SCHEMBL31420510 | 0.89 | PIK3C3 (0.51) | PIK3C3 | |
| SCHEMBL26686446 | 0.87 | AAK1 (0.44) | PIK3C3WNT3AMAPK1 | |
| SCHEMBL31420705 | 0.87 | AAK1 (0.44) | PIK3C3WNT3AMAPK1 | |
| SCHEMBL31420490 | 0.86 | PIK3C3 (0.52) | PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |