Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.46 |
| ▸ | FLT3 | P36888 | 3/20 | 0.45 |
| ▸ | PLK4 | O00444 | 3/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | MARK2 | Q7KZI7 | 3/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.45 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | LCK | P06239 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | KIT | P10721 | 2/20 | 0.45 |
| ▸ | FLT1 | P17948 | 2/20 | 0.45 |
| ▸ | FLT4 | P35916 | 2/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686005 | 1.00 | KDR (0.58) | KDRNTRK1JAK2MAPK1FLT3 | |
| SCHEMBL31240740 | 0.88 | JAK2 (0.47) | KDRNTRK1JAK2PLK4ROCK2 | |
| SCHEMBL26685861 | 0.86 | JAK2 (0.56) | KDRNTRK1JAK2MAPK1FLT3 | |
| SCHEMBL30633352 | 0.86 | JAK2 (0.56) | KDRNTRK1JAK2MAPK1FLT3 | |
| SCHEMBL30633305 | 0.85 | KDR (0.57) | KDRNTRK1JAK2MAPK1FLT3 | |
| SCHEMBL30633365 | 0.85 | KDR (0.62) | KDRNTRK1JAK2MAPK1FLT3 | |
| SCHEMBL26686045 | 0.85 | KDR (0.57) | KDRNTRK1JAK2MAPK1FLT3 | |
| SCHEMBL26685808 | 0.85 | KDR (0.62) | KDRNTRK1JAK2MAPK1FLT3 | |
| SCHEMBL31420120 | 0.85 | JAK2 (0.48) | KDRNTRK1JAK2MAPK1FLT3 | |
| SCHEMBL26685726 | 0.85 | JAK2 (0.48) | KDRNTRK1JAK2MAPK1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | claimed |
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |