SCHEMBL30634405

SCHEMBL30634405

COc1ccc2c(C)cc(=O)[nH]c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 1.00
ALDH1A1 P00352 6/20 0.68
RXFP1 Q9HBX9 1/20 0.68
GAA P10253 3/20 0.67
GLA P06280 2/20 0.67
HPGD P15428 3/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
TP53 P04637 1/20 0.59
TNKS2 Q9H2K2 4/20 0.56
HSD17B10 Q99714 1/20 0.56
CYP1A2 P05177 1/20 0.55
CYP2C19 P33261 1/20 0.55
AR P10275 1/20 0.53
NQO2 P16083 2/20 0.53
CDK4 P11802 1/20 0.53
CCND1 P24385 1/20 0.53
POLB P06746 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
CYP19A1 P11511 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394584 1.00 KDM4E (1.00) KDM4EALDH1A1RXFP1GAAGLA
SCHEMBL12002193 0.88 KDM4E (0.78) KDM4EALDH1A1RXFP1GAAGLA
SCHEMBL2798566 0.86 KDM4E (0.75) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL30283738 0.83 KDM4E (0.70) KDM4EALDH1A1RXFP1GAAGLA
SCHEMBL30283860 0.83 KDM4E (0.71) KDM4EALDH1A1RXFP1GAAGLA
SCHEMBL28445737 0.83 KDM4E (0.71) KDM4EALDH1A1RXFP1GAAGLA
SCHEMBL743131 0.83 KDM4E (0.71) KDM4EALDH1A1RXFP1GAAGLA
SCHEMBL12667324 0.81 KDM4E (0.69) KDM4EALDH1A1RXFP1GAAGLA
SCHEMBL12986903 0.80 KDM4E (1.00) KDM4EALDH1A1RXFP1GAAGLA
SCHEMBL10285854 0.79 KDM4E (0.65) KDM4EALDH1A1GAAGLAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119307334-A Low-corrosion and high-stability semiconductor chip cleaning solution and preparation method and application thereof 大连奥首科技有限公司 2025-01-14 CN claimed
EP-4511119-A1 COMPOUNDS ACTIVE TOWARDS BROMODOMAINS Nuevolution A/S (DK) 2025-02-26 EP disclosed
CN-119307334-A Low-corrosion and high-stability semiconductor chip cleaning solution and preparation method and application thereof 大连奥首科技有限公司 2025-01-14 CN disclosed
WO-2023205251-A1 COMPOUNDS ACTIVE TOWARDS BROMODOMAINS NUEVOLUTION A/S (DK) 2023-10-26 WO disclosed