Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 12/20 | 0.65 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212979 | 0.79 | CYP11B1 (1.00) | CYP11B1CYP11B2 | |
| SCHEMBL30634454 | 0.77 | CYP11B1 (0.67) | CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL30634470 | 0.77 | CYP11B1 (0.67) | CYP11B1CYP11B2 | |
| SCHEMBL30634453 | 0.75 | CYP11B1 (0.67) | CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL30634436 | 0.74 | CYP11B1 (0.55) | CYP11B1CYP11B2 | |
| SCHEMBL29599903 | 0.73 | CYP11B1 (0.40) | CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL30634465 | 0.73 | CYP11B1 (0.69) | CYP11B1CYP11B2 | |
| SCHEMBL30634455 | 0.73 | CYP11B1 (0.52) | CYP11B1CYP11B2 | |
| SCHEMBL30634446 | 0.73 | CYP11B1 (0.69) | CYP11B1CYP11B2 | |
| SCHEMBL17723869 | 0.72 | CYP11B1 (1.00) | CYP11B1CYP11B2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212636-B1 | NEW PYRIDINYLOXY- AND PHENYLOXY-PYRAZOLYL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2023-11-29 | — | — | EP | disclosed |