SCHEMBL30634449

SCHEMBL30634449

Cc1ccc(O/C(=C/N(C)C)C(=O)c2ccccc2Cl)cn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 20/20 1.00
CYP11B2 P19099 13/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17723958 1.00 CYP11B1 (1.00) CYP11B1CYP11B2
SCHEMBL17714262 0.89 CYP11B1 (1.00) CYP11B1CYP11B2
SCHEMBL17723944 0.89 CYP11B1 (1.00) CYP11B1CYP11B2
SCHEMBL17714261 0.89 CYP11B1 (1.00) CYP11B1CYP11B2
SCHEMBL17714259 0.83 CYP11B1 (1.00) CYP11B1CYP11B2
SCHEMBL19212869 0.83 CYP11B1 (1.00) CYP11B1CYP11B2
SCHEMBL30634452 0.83 CYP11B1 (1.00) CYP11B1CYP11B2
SCHEMBL17714260 0.83 CYP11B1 (1.00) CYP11B1CYP11B2
SCHEMBL17723915 0.81 CYP11B1 (0.81) CYP11B1CYP11B2
SCHEMBL19212976 0.79 CYP11B1 (0.65) CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3212636-B1 NEW PYRIDINYLOXY- AND PHENYLOXY-PYRAZOLYL COMPOUNDS HOFFMANN LA ROCHE (CH) 2023-11-29 EP disclosed