Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26670631 | 1.00 | CHEK1 (0.71) | CHEK1KCNH2 | |
| SCHEMBL23327341 | 0.89 | CHEK1 (0.62) | CHEK1KCNH2 | |
| SCHEMBL29788604 | 0.87 | CHEK1 (0.72) | CHEK1KCNH2 | |
| SCHEMBL23327373 | 0.87 | CHEK1 (0.62) | CHEK1KCNH2 | |
| SCHEMBL1973740 | 0.87 | CHEK1 (0.72) | CHEK1KCNH2 | |
| SCHEMBL23327503 | 0.87 | CHEK1 (0.62) | CHEK1KCNH2 | |
| SCHEMBL23327268 | 0.86 | CHEK1 (0.61) | CHEK1KCNH2 | |
| SCHEMBL23327328 | 0.86 | CHEK1 (0.61) | CHEK1KCNH2 | |
| Hydrochloric Acid SCHEMBL28560262 | 0.86 | CHEK1 (0.70) | CHEK1KCNH2 | |
| Hydrochloric Acid SCHEMBL1975059 | 0.85 | CHEK1 (0.69) | CHEK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532486-A1 | PYRIDINE CHECKPOINT KINASE 1 (CHK1) INHIBITORS AND USES THEREOF | Boundless Bio, Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-119546588-A | Pyridine checkpoint kinase 1 (CHK 1) inhibitors and uses thereof | 无界生物公司 | 2025-02-28 | — | — | CN | disclosed |
| WO-2023230477-A1 | PYRIDINE CHECKPOINT KINASE 1 (CHK1) INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. (US) | 2023-11-30 | — | — | WO | disclosed |