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SCHEMBL30635331

SCHEMBL30635331

CC(C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 19/20 0.60
▸ SCTR P47872 1/20 0.59
▸ BACE1 P56817 1/20 0.54
▸ BACE2 Q9Y5Z0 1/20 0.54
▸ GCGR P47871 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29462131 0.96 GLP1R (0.64) GLP1RSCTRBACE1BACE2GCGR
SCHEMBL30184796 0.96 GLP1R (0.64) GLP1RSCTRBACE1BACE2GCGR
SCHEMBL31740815 0.96 GLP1R (0.56) GLP1RSCTRGCGR
SCHEMBL30424020 0.94 GLP1R (0.64) GLP1RSCTR
SCHEMBL29372444 0.94 GLP1R (0.64) GLP1RSCTR
SCHEMBL31741239 0.94 GLP1R (0.55) GLP1RSCTRGCGR
SCHEMBL30637756 0.93 GLP1R (0.57) GLP1RSCTR
SCHEMBL31438929 0.93 GLP1R (0.66) GLP1RSCTR
SCHEMBL30049216 0.93 GLP1R (0.66) GLP1RSCTR
SCHEMBL30049031 0.93 GLP1R (0.66) GLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119060201-A Chemoenzymatic synthesis of liraglutide, soxhlet Ma Lutai and GLP-1 费森尤斯卡比有限公司 2024-12-03 — — CN disclosed
CN-111819191-B Chemoenzymatic synthesis of liraglutide, soxhlet Ma Lutai and GLP-1 费森尤斯卡比有限公司 2024-08-20 — — CN disclosed
CN-117750969-A Monomeric fusion peptides and methods of use thereof 雅利斯塔制药公司 2024-03-22 — — CN disclosed
EP-3704143-B1 CHEMO-ENZYMATIC SYNTHESIS OF LIRAGLUTIDE, SEMAGLUTIDE AND GLP-1 FRESENIUS KABI IPSUM S R L (IT) 2023-10-18 — — EP disclosed