Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.57 |
| ▸ | JAK1 | P23458 | 15/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31218707 | 1.00 | TYK2 (0.57) | TYK2JAK1CYP2C19KCNH2NUDT1 | |
| SCHEMBL30466384 | 0.93 | TYK2 (0.67) | TYK2JAK1CYP2C19 | |
| SCHEMBL30636414 | 0.88 | TYK2 (0.61) | TYK2JAK1CYP2C19 | |
| SCHEMBL30490080 | 0.87 | TYK2 (0.49) | TYK2JAK1CYP2C19KCNH2 | |
| SCHEMBL29883074 | 0.84 | TYK2 (0.52) | TYK2JAK1CYP2C19KCNH2 | |
| SCHEMBL24899888 | 0.84 | TYK2 (0.63) | TYK2JAK1CYP2C19KCNH2 | |
| SCHEMBL30392752 | 0.84 | TYK2 (0.63) | TYK2JAK1CYP2C19KCNH2 | |
| SCHEMBL30392632 | 0.84 | TYK2 (0.63) | TYK2JAK1CYP2C19KCNH2 | |
| SCHEMBL30393144 | 0.84 | TYK2 (0.63) | TYK2JAK1CYP2C19KCNH2 | |
| SCHEMBL26102083 | 0.84 | TYK2 (0.63) | TYK2JAK1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213308-A1 | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF | 苏州隆博泰药业有限公司 | 2023-11-09 | — | — | WO | claimed |
| CN-119013277-A | TYK2 degrading agent and application thereof | 凯麦拉医疗公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023213308-A1 | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF | 苏州隆博泰药业有限公司 | 2023-11-09 | — | — | WO | disclosed |