SCHEMBL30637997

SCHEMBL30637997

CCOC(=O)c1cc2c([nH]1)CC[C@]1(C2)C(=O)Nc2ncccc21

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CALCRL Q16602 14/20 0.41
▸ ADM2 Q7Z4H4 3/20 0.40
▸ RAMP1 O60894 8/20 0.40
▸ CALCB P10092 2/20 0.40
▸ KCNH2 Q12809 1/20 0.39
▸ CALCA P06881 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30637925 1.00 CALCRL (0.41) CALCRLADM2RAMP1CALCBKCNH2
SCHEMBL30637931 1.00 CALCRL (0.41) CALCRLADM2RAMP1CALCBKCNH2
SCHEMBL30637900 1.00 CALCRL (0.41) CALCRLADM2RAMP1CALCBKCNH2
SCHEMBL30637904 1.00 CALCRL (0.41) CALCRLADM2RAMP1CALCBKCNH2
SCHEMBL26619165 1.00 CALCRL (0.41) CALCRLADM2RAMP1CALCBKCNH2
SCHEMBL30637938 0.91 CALCRL (0.44) CALCRLADM2RAMP1CALCBCALCA
SCHEMBL26619286 0.91 CALCRL (0.44) CALCRLADM2RAMP1CALCBCALCA
SCHEMBL26619455 0.86 CALCRL (0.41) CALCRLADM2RAMP1CALCBCALCA
SCHEMBL30637887 0.86 CALCRL (0.41) CALCRLADM2RAMP1CALCBCALCA
SCHEMBL30683665 0.84 CALCRL (0.40) CALCRLADM2RAMP1CALCBCALCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353860-A1 PIPERIDINE CARBOXAMIDE AZAINDANE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF BRISE PHARMACEUTICALS CO., LTD. (CN) 2025-11-20 — — US disclosed
EP-4516793-A1 PIPERIDINE CARBOXAMIDE AZAINDANE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF Brise Pharmaceuticals Co., Ltd. (CN) 2025-03-05 — — EP disclosed
CN-117003762-A Piperidine formamide aza indane derivative, preparation method and application thereof 熙源安健医药(上海)有限公司 2023-11-07 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353860-A1 PIPERIDINE CARBOXAMIDE AZAINDANE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF CALCR, CNR2, CALCRL CALCRL 3/4885ADM2 133/4885RAMP1 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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