SCHEMBL30639342

SCHEMBL30639342

[O-][S@@+]1CCc2nc(Cl)nc(NC3(CO)CCC3)c21

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LATS1 O95835 2/20 0.32
▸ LATS2 Q9NRM7 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30639341 1.00 LATS1 (0.32) LATS1LATS2
SCHEMBL31571836 1.00 LATS1 (0.32) LATS1LATS2
SCHEMBL14734142 1.00 LATS1 (0.32) LATS1LATS2
SCHEMBL29576569 0.97 LATS1 (0.32) LATS1LATS2
SCHEMBL373792 0.95 — —
SCHEMBL31491332 0.95 — —
SCHEMBL30678865 0.94 LATS1 (0.32) LATS1LATS2
SCHEMBL30678840 0.94 LATS1 (0.32) LATS1LATS2
SCHEMBL30678848 0.94 LATS1 (0.32) LATS1LATS2
SCHEMBL31622416 0.90 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023241684-A1 PDE4B INHIBITOR 武汉人福创新药物研发中心有限公司 2023-12-21 — — WO disclosed
CN-117247395-A PDE4B inhibitors 武汉人福创新药物研发中心有限公司 2023-12-19 — — CN disclosed
Send feedback