Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27129480 | 1.00 | AAK1 (0.42) | AAK1RENMMP13CTSLCTSB | |
| SCHEMBL27032791 | 1.00 | AAK1 (0.42) | AAK1RENMMP13CTSLCTSB | |
| SCHEMBL24093716 | 0.85 | AAK1 (0.49) | AAK1RENMMP13CTSLCTSB | |
| SCHEMBL23005858 | 0.85 | AAK1 (0.49) | AAK1RENMMP13CTSLCTSB | |
| SCHEMBL29097004 | 0.85 | AAK1 (0.42) | AAK1RENMMP13MME | |
| SCHEMBL27032815 | 0.85 | AAK1 (0.42) | AAK1RENMMP13MME | |
| SCHEMBL29828824 | 0.85 | AAK1 (0.42) | AAK1RENMMP13MME | |
| SCHEMBL30790784 | 0.84 | AAK1 (0.41) | AAK1RENMMP13 | |
| SCHEMBL30916039 | 0.84 | AAK1 (0.41) | AAK1RENMMP13 | |
| SCHEMBL29828542 | 0.84 | AAK1 (0.41) | AAK1RENMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981672-A | Macrocyclic compounds as CFTR modulators | 爱杜西亚药品有限公司 | 2023-10-31 | — | — | CN | disclosed |