Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29828809 | 1.00 | ATM (0.47) | ATMAAK1HDAC3HDAC4HDAC1 | |
| SCHEMBL29096959 | 1.00 | ATM (0.47) | ATMAAK1HDAC3HDAC4HDAC1 | |
| SCHEMBL27133393 | 0.90 | MAPK1 (0.39) | — | |
| SCHEMBL27032865 | 0.90 | MAPK1 (0.39) | — | |
| SCHEMBL27135967 | 0.89 | ATM (0.47) | ATMAAK1HDAC3HDAC4HDAC1 | |
| SCHEMBL27032864 | 0.89 | ATM (0.47) | ATMAAK1HDAC3HDAC4HDAC1 | |
| SCHEMBL29097261 | 0.86 | CYP3A4 (0.48) | ATMAAK1HDAC3HDAC4HDAC1 | |
| SCHEMBL29828762 | 0.86 | CYP3A4 (0.48) | ATMAAK1HDAC3HDAC4HDAC1 | |
| SCHEMBL30639635 | 0.86 | CYP3A4 (0.48) | ATMAAK1HDAC3HDAC4HDAC1 | |
| SCHEMBL29828533 | 0.85 | ATM (0.43) | ATMAAK1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119907667-A | Combination of macrocyclic CFTR modulators with CFTR corrector and/or CFTR potentiator | 爱杜西亚药品有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-116981672-A | Macrocyclic compounds as CFTR modulators | 爱杜西亚药品有限公司 | 2023-10-31 | — | — | CN | disclosed |