Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26621884 | 1.00 | NPC1 (0.43) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL26621850 | 0.87 | NPC1 (0.39) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL26621894 | 0.81 | NPC1 (0.44) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL26621863 | 0.80 | NPC1 (0.37) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL26621906 | 0.78 | NPC1 (0.35) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL26621843 | 0.78 | NPC1 (0.35) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL26621907 | 0.78 | NPC1 (0.41) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL26621877 | 0.78 | NPC1 (0.41) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL30640502 | 0.78 | NPC1 (0.41) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL30640454 | 0.77 | NPC1 (0.36) | NPC1RAB9AKMT2AMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023214325-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AND USES THEREOF AS TET2 INHIBITORS | NOVARTIS AG (CH) | 2023-11-09 | — | — | WO | disclosed |