Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30615200 | 0.98 | KDM4E (0.47) | KDM4ELMNAMMP2TSHRTDP1 | |
| SCHEMBL1704390 | 0.83 | KDM4E (0.55) | KDM4ELMNAMMP2TSHRTDP1 | |
| SCHEMBL5462444 | 0.81 | PARP1 (0.61) | KDM4ELMNAMMP2TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL30632614 | 0.81 | KDM4E (0.53) | KDM4ELMNAMMP2TSHRTDP1 | |
| SCHEMBL1586020 | 0.77 | KDM4E (0.44) | KDM4ELMNAMMP2TSHRTDP1 | |
| SCHEMBL927409 | 0.76 | CNR2 (0.53) | LMNATSHRTP53CYP3A4MAPT | |
| SCHEMBL1164312 | 0.76 | PARP1 (0.68) | KDM4ELMNAMMP2TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL5126803 | 0.74 | PARP1 (0.66) | KDM4ELMNAMMP2TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL9684991 | 0.74 | CNR2 (0.51) | LMNATSHRTP53CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL30615213 | 0.74 | PARP1 (0.66) | KDM4ELMNAMMP2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062816-A | Tricyclic-amide-bicyclic PRMT5 inhibitors | 美国安进公司 | 2023-11-14 | — | — | CN | disclosed |