⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18358867 | 1.00 | — | — | |
| SCHEMBL1068577 | 1.00 | — | — | |
| SCHEMBL18358856 | 0.92 | — | — | |
| SCHEMBL18358855 | 0.92 | — | — | |
| SCHEMBL18358863 | 0.92 | — | — | |
| SCHEMBL6624662 | 0.81 | — | — | |
| SCHEMBL132899 | 0.81 | — | — | |
| SCHEMBL4354716 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL9855170 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL9855179 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9090593-B2 | Bicyclic compounds as Pim inhibitors | AMGEN INC. (US) | 2015-07-28 | — | — | US | claimed |
| US-20140031360-A1 | BICYCLIC COMPOUNDS AS PIM INHIBITORS | AMGEN INC. (US) | 2014-01-30 | — | — | US | claimed |
| EP-2649065-A1 | BICYCLIC COMPOUNDS AS PIM INHIBITORS | Amgen Inc. (US) | 2013-10-16 | — | — | EP | claimed |
| WO-2012078777-A1 | BICYCLIC COMPOUNDS AS PIM INHIBITORS | AMGEN INC. (US) | 2012-06-14 | — | — | WO | claimed |
| US-7166594-B2 | Antibacterial activity | AVENTIS PHARMA S.A. (FR) | 2007-01-23 | — | — | US | claimed |
| US-6815437-B1 | VIRGINIAMYCINS AS BACTERICIDES; PRISTINAMYCIN CHEMICAL INTERMEDIATES | AVENTIS PHARMA S.A. (FR) | 2004-11-09 | — | — | US | claimed |
| EP-0135410-B1 | SYNERGISTIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1988-09-21 | — | — | EP | claimed |
| US-4618599-A | WATER SOLUBILITY | RHONE-POULENC SANTE (FR) | 1986-10-21 | — | — | US | claimed |
| US-20250177330-A1 | Use of Thiol Compounds to Treat Neurological Disease | MERCAPTOR DISCOVERIES, INC. | 2025-06-05 | — | — | US | disclosed |
| US-12128014-B2 | Use of thiol compounds to treat neurological disease | MERCAPTOR DISCOVERIES, INC. (US) | 2024-10-29 | — | — | US | disclosed |
| EP-3615013-B1 | THIOL COMPOUNS FOR TREATING ACUTE TRAUMATIC BRAIN INJURY | MERCAPTOR DISCOVERIES INC (US) | 2024-08-14 | — | — | EP | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |
| US-20230210846-A1 | TREATMENT FOR AMYLOIDOSIS | ZENO MANAGEMENT, INC. | 2023-07-06 | — | — | US | disclosed |
| US-20230115413-A1 | Use of Thiol Compounds to Treat Neurological Disease | ZANKEL, TODD C, MR | 2023-04-13 | — | — | US | disclosed |
| EP-0787728-A1 | Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-08-06 | — | — | EP | disclosed |
| EP-0708091-A2 | Indoloylguanidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-4618599-A | WATER SOLUBILITY | RHONE-POULENC SANTE (FR) | 1986-10-21 | — | — | US | disclosed |
| US-4618599-A | WATER SOLUBILITY | RHONE-POULENC SANTE (FR) | 1986-10-21 | — | — | US | disclosed |
| US-4617377-A | BACTERICIDES | RHONE-POULENC SANTE (FR) | 1986-10-14 | — | — | US | disclosed |
| US-4590004-A | MICROBIOCIDES | RHONE-POULENC SANTE (FR) | 1986-05-20 | — | — | US | disclosed |