⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634138 | 0.96 | — | — | |
| SCHEMBL30643171 | 0.92 | — | — | |
| SCHEMBL30643172 | 0.92 | — | — | |
| SCHEMBL10642979 | 0.76 | — | — | |
| SCHEMBL3067270 | 0.64 | — | — | |
| SCHEMBL3067267 | 0.64 | — | — | |
| SCHEMBL3067274 | 0.64 | — | — | |
| SCHEMBL22130166 | 0.61 | — | — | |
| SCHEMBL9688972 | 0.59 | — | — | |
| SCHEMBL5480528 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250276969-A1 | 2-(5-FLUORO-1-(2-FLUOROBENZYL)-1H-PYRAZOLO[3,4-b]PYRIDIN-3-YL)-5-NITROSOPYRIMIDIN-4,6-DIAMINE OR A SALT THEREOF, METHOD FOR THE PREPARATION THEREOF, AND USE THEREOF IN THE SYNTHESIS OF VERICIGUAT | MOEHS IBERICA, S.L. (ES) | 2025-09-04 | — | — | US | disclosed |
| EP-4519262-A1 | 2-(5-FLUORO-1-(2-FLUOROBENZYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YL)-5-NITROSOPYRIMIDIN-4,6-DIAMINE OR A SALT THEREOF, METHOD FOR THE PREPARATION THEREOF, AND USE THEREOF IN THE SYNTHESIS OF VERICIGUAT | Moehs Ibérica, S.L. (ES) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213525-A1 | 2-(5-FLUORO-1-(2-FLUOROBENZYL)-1H-PYRAZOLO[3,4-b]PYRIDIN-3-YL)-5-NITROSOPYRIMIDIN-4,6-DIAMINE OR A SALT THEREOF, METHOD FOR THE PREPARATION THEREOF, AND USE THEREOF IN THE SYNTHESIS OF VERICIGUAT | MOEHS IBERICA, S.L. (ES) | 2023-11-09 | — | — | WO | disclosed |