Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.61 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.61 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26641267 | 1.00 | CRBN (0.61) | CRBNDDB1NAMPTKDM4EMAPT | |
| SCHEMBL24206650 | 0.95 | CRBN (0.67) | CRBNDDB1NAMPTKDM4EMAPT | |
| SCHEMBL23301622 | 0.95 | CRBN (0.67) | CRBNDDB1NAMPTKDM4EMAPT | |
| SCHEMBL25187964 | 0.95 | CRBN (0.67) | CRBNDDB1NAMPTKDM4EMAPT | |
| SCHEMBL31062846 | 0.94 | DDB1 (0.59) | CRBNDDB1NAMPTGPR119HRH3 | |
| SCHEMBL30643616 | 0.91 | DDB1 (0.61) | CRBNDDB1NAMPTKDM4EMAPT | |
| SCHEMBL31134647 | 0.88 | DDB1 (0.59) | CRBNDDB1MAPTGPR119 | |
| SCHEMBL25169785 | 0.88 | DDB1 (0.69) | CRBNDDB1NAMPTMAPT | |
| SCHEMBL24671233 | 0.86 | CRBN (0.58) | CRBNDDB1NAMPTKDM4EMAPT | |
| SCHEMBL25184167 | 0.86 | CRBN (0.58) | CRBNDDB1NAMPTKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120092003-A | CDK protein degrading agents, pharmaceutical compositions and therapeutic uses | 拜欧斯瑞克斯公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2024168096-A2 | PDE4 DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |